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Cytokine responses in virus infections: effects on pathogenesis, recovery and persistence.

Authors
  • Estcourt, M J
  • Ramshaw, l A
  • Ramsay, A J
Type
Published Article
Journal
Current Opinion in Microbiology
Publisher
Elsevier
Publication Date
Aug 01, 1998
Volume
1
Issue
4
Pages
411–418
Identifiers
PMID: 10066517
Source
Medline
License
Unknown

Abstract

During the past year, significant advances have been made in our understanding of cytokine regulation and the respective roles played by T helper cells type 1 and 2 immune responses during virus infection. Numerous mechanisms by which viruses may evade host immune defences have now been identified, some directly influencing cytokine activity. Major advances have also been made in delineating the roles of cytokines and chemokines at different stages in the pathogenesis of HIV infection.

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