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Cytogenetics of Abelson virus-induced malignant lymphoma cell lines in the mouse.

Authors
Type
Published Article
Journal
Cancer Genetics and Cytogenetics
0165-4608
Publisher
Elsevier
Publication Date
Volume
28
Issue
1
Pages
119–125
Identifiers
PMID: 3496951
Source
Medline
License
Unknown

Abstract

Cytogenetic studies were performed on 11 established murine thymoma or peripheral lymphoma cell lines induced by a thymotropic Abelson virus. In eight cell lines a trisomy 5 was present, whereas, two cell lines had a normal karyotype like fresh tumor cells. In the last cell line a trisomy 11 resulting from a t(5;11) was observed. The origin of this nonrandom chromosome abnormality is briefly discussed.

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