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Cytochemical localization of adenylate-cyclase in embryonic mouse molars.

Authors
  • Osman, M
  • Meyer, J M
  • Staubli, A
  • Ruch, J V
Type
Published Article
Journal
Acta Histochemica
Publisher
Elsevier
Publication Date
Jan 01, 1981
Volume
68
Issue
1
Pages
91–102
Identifiers
PMID: 6789596
Source
Medline
License
Unknown

Abstract

The cytochemical method of HOWELL and WHITFIELD (1972) and the revised cytochemical medium of KEMPEN et al. (1978) has been used to investigate the localization of adenylate-cyclase activity in 18, 19 and 20 day old first embryonic mandibular molars. Membrane associated precipitate granules were observed in preameloblasts and odontoblasts localized in the area where preodontoblasts become post-mitotic. Heat inactived teeth and the samples incubated in media without substrate were negative for membrane bound lead deposits. A correlation may exist between high adenylate-cyclase activity and the terminal differentiation of odontoblasts.

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