CYP5122A1, a novel cytochrome P450 is essential for survival of Leishmania donovani
- Authors
-
- verma, s.
- mehta, a.
- shaha, c.
- Publication Date
- Jan 01, 2011
- Source
- ScholarBank@NUS
- Keywords
-
- Amphotericin B
- Antimony
- Calcium Ion
- Cytochrome P450
- Cytochrome P450 5122A1
- Ergosterol
- Miltefosine
- Neomycin
- Unclassified Drug
- Adenosine Triphosphate
- Cytochrome P450
- Protozoal Protein
- Reactive Oxygen Metabolite
- Allele
- Article
- Controlled Study
- Endoplasmic Reticulum
- Enzyme Activity
- Enzyme Localization
- Glycosome
- Hamster
- In Vitro Study
- In Vivo Study
- Leishmania Donovani
- Macrophage
- Mass Fragmentography
- Membrane Potential
- Mitochondrion
- Nonhuman
- Parasite Survival
- Phenotype
- Promastigote
- Protein Expression
- Wild Type
- Animal
- Classification
- Drug Effect
- Genetics
- Genome
- Immunohistochemistry
- Metabolism
- Parasitology
- Pathogenicity
- Phylogeny
- Polyacrylamide Gel Electrophoresis
- Syrian Hamster
- Visceral Leishmaniasis
- Western Blotting
- Cricetinae
- Leishmania Donovani
- Adenosine Triphosphate
- Animals
- Blotting, Western
- Cricetinae
- Cytochrome P-450 Enzyme System
- Electrophoresis, Polyacrylamide Gel
- Ergosterol
- Genome, Protozoan
- Immunohistochemistry
- Leishmania Donovani
- Leishmaniasis, Visceral
- Mesocricetus
- Mitochondria
- Phylogeny
- Protozoan Proteins
- Reactive Oxygen Species
- License
- Green
- External links
Abstract
10.1371/journal.pone.0025273 / PLoS ONE / 6 / 9 / e25273
