Cyclosporine for corticosteroid-refractory acute generalized exanthematous pustulosis due to hydroxychloroquine.
Department of Dermatology, University of South Florida Morsani College of Medicine, Tampa, Florida.
Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.
- Published Article
Wiley (Blackwell Publishing)
- Publication Date
Sep 01, 2018
Acute generalized exanthematous pustulosis most often manifests 1-2 days following exposure to a characteristic drug, such as aminopenicillins, calcium-channel blockers, or terbinafine. Recovery is usually rapid following drug withdrawal, and systemic corticosteroids represent the historic treatment of choice. Herein, acute generalized exanthematous pustulosis incited by hydroxychloroquine is briefly reviewed: a prolonged latency and recalcitrance to corticosteroids are noteworthy. In this unique context, cyclosporine tapered over several months is an effective therapeutic option. © 2018 Wiley Periodicals, Inc.
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This record was last updated on 10/20/2019 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/30152569