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Cyclosporin-induced remission in an infant with alkylating agents-resistant nephrotic syndrome. A case report.

Authors
  • Yilmaz, G G
  • Güven, A G
Type
Published Article
Journal
The Turkish Journal of Pediatrics
Publisher
The Turkish Journal of Pediatrics
Publication Date
Jan 01, 1995
Volume
37
Issue
4
Pages
411–414
Identifiers
PMID: 8560611
Source
Medline
License
Unknown

Abstract

The efficacy of cyclosporin-A, a potent immunosuppressive agent, has not been clearly proven in the management of childhood nephrotic syndrome. The occurrence of early relapse as the dose of cyclosporin is tapered or as soon as the drug is stopped and the potential nephrotoxic effects of prolonged treatment have caused it to be used in limited cases. We report an eighteen-month-old boy with steroid toxicity and alkylating agents-resistant nephrotic syndrome, who subsequently went very quickly into remission lasting at least one year after receiving cyclosporin-A for only three months.

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