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Cyclic AMP level in red blood cells of Plasmodium berghei-infected Mastomys natalensis.

Authors
  • Khare, S
  • Ghatak, S
Type
Published Article
Journal
Experientia
Publication Date
Mar 15, 1991
Volume
47
Issue
3
Pages
236–238
Identifiers
PMID: 1849086
Source
Medline
License
Unknown

Abstract

The present report describes the changes in cyclic AMP level which occur upon parasitization of red cells by Plasmodium berghei. Parasitized erythrocytes were separated from the non-parasitized population by percoll density-gradient centrifugation. An increase in the cyclic AMP content of both non-parasitized and parasitized erythrocytes of infected animals compared with that of uninfected animals was observed. The patterns of physiological response to isoproterenol in normal, parasitized and non-parasitized erythrocytes were identical.

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