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[Cyclic adenosine monophosphate (3'5' cAMP) in the alcohol withdrawal syndrome. Clinico-pathogenetic perspectives].

Authors
  • Nardoni, A
  • Geatti, O
  • Marchetti, E
  • Di Piazza, V
  • Sabatini, E
Type
Published Article
Journal
Minerva medica
Publication Date
Feb 11, 1984
Volume
75
Issue
5
Pages
191–195
Identifiers
PMID: 6322056
Source
Medline
License
Unknown

Abstract

The cyclic adenosine monophosphate (AMP-c) excreted in the urine over a 24 hour period was systematically measured in 40 patients suffering from alcohol withdrawal syndrome (AWS) in varying degrees from slight to delirium tremens. In almost all patients the level of excreted AMP-c was high bul returned to normal when the clinical picture together with arterial pressure and cardiac frequency, was normalised. This shows the primary importance of the central sympathetic-adrenergic system in the pathogenesis of AWS and the value of monitoring urinary AMP-c excretion during the syndrome.

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