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Cutaneous macroglobulinosis. A case report with unique ultrastructural findings.

Authors
  • Lowe, L
  • Fitzpatrick, J E
  • Huff, J C
  • Shanley, P F
  • Golitz, L E
Type
Published Article
Journal
Archives of Dermatology
Publisher
American Medical Association
Publication Date
Mar 01, 1992
Volume
128
Issue
3
Pages
377–380
Identifiers
PMID: 1550371
Source
Medline
License
Unknown

Abstract

Cutaneous macroglobulinosis may be a rare presenting sign of Waldenström's macroglobulinemia. Deposits of macroglobulin in the skin result in a histologic picture that greatly resembles amyloid. Histochemical stains, direct immunofluorescence microscopy, and electron microscopy are useful tools that enable accurate diagnosis and help to distinguish cutaneous macroglobulinosis from other deposition disorders.

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