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Current treatment of chronic beryllium disease.

Authors
  • Sood, Akshay
Type
Published Article
Journal
Journal of Occupational and Environmental Hygiene
Publisher
Informa UK (Taylor & Francis)
Publication Date
Dec 01, 2009
Volume
6
Issue
12
Pages
762–765
Identifiers
DOI: 10.1080/15459620903158698
PMID: 19894178
Source
Medline
License
Unknown

Abstract

The current mainstay of management of chronic beryllium disease involves cessation of beryllium exposure and use of systemic corticosteroids. However, there are no randomized controlled trials to assess the effect of these interventions on the natural history of this disease. Despite this limitation, it is prudent to remove patients with chronic beryllium disease from further exposure and consider treating progressive disease early with long-term corticosteroids. The effect of treatment should be monitored using pulmonary function tests and high-resolution computed tomography of the chest. However, once pulmonary fibrosis has developed, corticosteroid therapy cannot reverse the damage.

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