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Current status of chemotherapy for advanced gastric cancer.

Authors
Type
Published Article
Journal
Anticancer research
Publication Date
Volume
7
Issue
4B
Pages
755–759
Identifiers
PMID: 3314675
Source
Medline

Abstract

A review of the current status of chemotherapy in advanced gastric cancer is presented. Results of recent randomized trials have questioned the merits of the most commonly used chemotherapy protocols such as combinations of 5-fluorouracil (5-FU) and doxorubicin with mitomycin C or a nitrosourea (FAM, MeFA, FAB) over 5-FU alone. Results of new ("second generation") protocols and the impact of these results on future trials in an adjuvant setting and in advanced disease are discussed. For the time being no "standard" chemotherapy can be advocated and patients should preferably be treated in clinical trials.

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