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Current concepts in the surgical treatment of skeletal metastases

Authors
  • Ehne, Jessica
  • Tsagozis, Panagiotis
Type
Published Article
Journal
World Journal of Orthopedics
Publisher
Baishideng Publishing Group Co (World Journal of Orthopedics)
Publication Date
Jul 18, 2020
Volume
11
Issue
7
Pages
319–327
Identifiers
DOI: 10.5312/wjo.v11.i7.319
PMID: 32908816
PMCID: PMC7441493
Source
PubMed Central
Keywords
License
Green

Abstract

Symptomatic metastatic bone disease affects a large proportion of patients with malignant tumours and significantly impairs patients’ quality of life. There are still controversies regarding both surgical indications and methods, mainly because of the relatively few high-quality studies in this field. Generally, prosthetic reconstruction has been shown to result in fewer implant failures and should be preferred in patients with a good prognosis. Survival estimation tools should be used as part of preoperative planning. Adjuvant treatment, which relies on radiotherapy and inhibition of osteoclast function may also offer symptomatic relief and prevent implant failure. In this review we discuss the epidemiology, indications for surgery, preoperative planning, surgical techniques and adjuvant treatment of metastatic bone disease.

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