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Current applications of precision medicine: a bibliometric analysis.

Authors
  • Williams, Jessica R1
  • Lorenzo, Dalia2, 3
  • Salerno, John4
  • Yeh, Vivian M5, 6
  • Mitrani, Victoria B2
  • Kripalani, Sunil5, 6
  • 1 School of Nursing, University of North Carolina at Chapel Hill, NC 27599, USA.
  • 2 School of Nursing & Health Studies, University of Miami, FL 33146, USA.
  • 3 Center for Research, Baptist Health South Florida, FL 33143, USA.
  • 4 Department of Behavioral & Community Health, School of Public Health, University of Maryland College Park, MD 20742, USA.
  • 5 Center for Clinical Quality & Implementation Research, Vanderbilt University Medical Center, TN 37203, USA.
  • 6 Division of General Internal Medicine & Public Health, Department of Medicine, Vanderbilt University Medical Center, TN 37232, USA.
Type
Published Article
Journal
Personalized medicine
Publication Date
Jul 01, 2019
Volume
16
Issue
4
Pages
351–359
Identifiers
DOI: 10.2217/pme-2018-0089
PMID: 31267841
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

A bibliometric analysis was conducted to describe trends in the publication of precision medicine literature over time. Searches identified 5552 articles with exponential growth from 2012 to 2018. Most were published in medical specialty journals, particularly oncology. Precision medicine definitions focused on tailored/individualized/personalized treatments and genetics/biology. Little attention was given to social and environmental determinants of health and health disparities. To fulfill the promise of precision medicine to positively impact broad populations, work is needed to develop the science of precision medicine for addressing health disparities and social and environmental determinants of health. While some precision medicine definitions include all factors that contribute to individual differences in health (e.g., genes, environments and lifestyles), future empirical work that includes and integrates all three areas is also required.

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