Affordable Access

deepdyve-link
Publisher Website

Cure of beta-thalassaemia major by umbilical cord blood transplantation--a case report of Malaysia's first cord blood transplantation.

Authors
  • Chan, L L1
  • Lin, H P
  • 1 Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia. [email protected] , (Malaysia)
Type
Published Article
Journal
Journal of tropical pediatrics
Publication Date
Aug 01, 1999
Volume
45
Issue
4
Pages
243–245
Identifiers
DOI: 10.1093/tropej/45.4.243
PMID: 10467839
Source
Medline
License
Unknown

Abstract

A 25-month-old boy with beta-thalassaemia major was presented with an opportunity for umbilical cord blood transplantation when his unborn sibling was diagnosed in utero to be a beta-thalassaemia carrier and also human leucocyte antigen compatible. A barely adequate amount of cord blood was collected at the birth of his sibling and infused into the patient after appropriate chemo-conditioning. Engraftment occurred without major complications. The subject is now alive and well 9 months post-transplant, thus marking our first success in umbilical cord blood transplantation.

Report this publication

Statistics

Seen <100 times