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CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure.

Authors
  • 1
Type
Published Article
Journal
Neurology
Publication Date
Volume
50
Issue
6
Pages
1869–1871
Identifiers
PMID: 9633746
Source
Medline

Abstract

Carnitine concentrations in CSF, serum, and urine in normal febrile children and children with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF were 1/10 compared with serum in normal febrile children. These levels increased two- to three-fold in the pathologic conditions studied. Since damage to the blood-brain barrier occurs in these conditions, higher blood-brain barrier permeability might explain CNS carnitine accumulation.

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