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Cryo-EM structures tell a tale of two telomerases

Authors
  • Forino, Nicholas M.1
  • Hentschel, Jendrik1
  • Stone, Michael D.1, 1
  • 1 University of California, Santa Cruz, Santa Cruz, CA, USA , Santa Cruz (United States)
Type
Published Article
Journal
Nature Structural & Molecular Biology
Publisher
Springer Nature
Publication Date
May 28, 2021
Volume
28
Issue
6
Pages
457–459
Identifiers
DOI: 10.1038/s41594-021-00611-8
Source
Springer Nature
Disciplines
  • news-and-views
License
Yellow

Abstract

New atomic-resolution structures provide detailed insights into the molecular mechanism of telomerase, ushering in a new era of rational drug design to target telomerase in human genetic disorders and cancer.

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