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Crossmatch difficulties following the prophylactic use of Rh immune globulin.

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Abstract

With increasing demand for platelet transfusion the need to use platelets from Rh-positive persons for Rh-negative individuals often arises. The administration of Rho(D) immune globulin (human) in this situation has been recommended, but may cause serologic difficulties owing to the recipient's passive acquisition of antibodies other than anti-D.

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