Crosscurrents in HIV-1 evolution
- Authors
- Type
- Published Article
- Journal
- Nature Immunology
- Publisher
- Springer Nature
- Publication Date
- Feb 01, 2006
- Volume
- 7
- Issue
- 2
- Pages
- 121–122
- Identifiers
- DOI: 10.1038/ni0206-121
- Source
- Springer Nature
- License
- Yellow
Abstract
Substitutions in CD8+ T cell epitopes in viral proteins can alter the complex interaction between viruses and host immunity. Reduced viral fitness and recognition of altered and subdominant epitopes are possible outcomes.