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Cross-talk between receptors coupled to calcium currents in adult but not neonatal rat sensory neurons.

Authors
Type
Published Article
Journal
Cell biology international reports
Publication Date
Volume
13
Issue
12
Pages
1165–1175
Identifiers
PMID: 2561467
Source
Medline
License
Unknown

Abstract

In adult rat sensory neurons Ca2+ currents were studied with the whole-cell patch-clamp technique. Two categories of neuromodulators, known to activate different 2nd messenger systems: 1) angiotensin II (AII), bovine serum albumin (BSA), Acetylcholine (ACh) and 2) GABA, stimulated the low-voltage activated (LVA) and inhibited the high voltage activated (HVA) currents, respectively. The simultaneous application of the two types of drugs failed to inhibit the HVA current via a putative cross-talk between the two 2nd messengers.

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