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A critical review: traditional uses, phytochemistry, pharmacology and toxicology of Stephania tetrandra S. Moore (Fen Fang Ji)

Authors
  • Jiang, Yueping1, 1, 1
  • Liu, Min1, 1, 1
  • Liu, Haitao1, 1, 1
  • Liu, Shao1, 1, 1
  • 1 Central South University,
Type
Published Article
Journal
Phytochemistry Reviews
Publisher
Springer-Verlag
Publication Date
Apr 24, 2020
Pages
1–41
Identifiers
DOI: 10.1007/s11101-020-09673-w
PMID: 32336965
PMCID: PMC7180683
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown

Abstract

Abstract Stephania tetrandra S. Moore ( S. tetrandra ) is distributed widely in tropical and subtropical regions of Asia and Africa. The root of this plant is known in Chinese as “Fen Fang Ji”. It is commonly used in traditional Chinese medicine to treat arthralgia caused by rheumatism, wet beriberi, dysuria, eczema and inflamed sores. Although promising reports have been published on the various chemical constituents and activities of S. tetrandra , no review comprehensively summarizes its traditional uses, phytochemistry, pharmacology and toxicology. Therefore, the review aims to provide a critical and comprehensive evaluation of the traditional use, phytochemistry, pharmacological properties, pharmacokinetics and toxicology of S. tetrandra in China, and meaningful guidelines for future investigations. Graphic abstract

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