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C-reactive protein gene polymorphisms (rs1205) in Asian Indian patients with Takayasu arteritis: Associations and phenotype correlations.

Authors
  • Nair, Aswin M1
  • Goel, Ruchika1
  • Hindhumati, Mohan1
  • Shah, Krati2
  • Chandana, Puneet3
  • Jayaseelan, Visalakshi4
  • Jayakanthan, Kabeerdoss1
  • Joseph, George5
  • Danda, Sumita6
  • Danda, Debashish1
  • 1 Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India. , (India)
  • 2 ONE Centre for Rheumatology and Genetics, Vadodara, Gujarat, India. , (India)
  • 3 AceProbe Technologies (India) Pvt. Ltd, Delhi, National Capital Territory, India. , (India)
  • 4 Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India. , (India)
  • 5 Department of Cardiology, Christian Medical College, Vellore, Tamil Nadu, India. , (India)
  • 6 Department of Clinical Genetics, Christian Medical College, Vellore, Tamil Nadu, India. , (India)
Type
Published Article
Journal
International Journal of Rheumatic Diseases
Publisher
Wiley (Blackwell Publishing)
Publication Date
Oct 11, 2017
Identifiers
DOI: 10.1111/1756-185X.13180
PMID: 29024426
Source
Medline
Keywords
License
Unknown

Abstract

T allele of rs1205 in CRP gene was less frequent in TA. CC genotype was associated with involvement of coronary arteries and ascending aorta. CC genotype was less commonly associated with blunted CRP response (CT + TT > CC).

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