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COX-2 dependent inflammation increases spinal Fos expression during rodent postoperative ileus

Authors
Publisher
Copyright 2003 by Gut
Publication Date
Source
PMC
Keywords
  • Inflammation And Motility

Abstract

Background and aims: Cyclooxygenase 2 (COX-2) and prostaglandins (PGs) participate in the pathogenesis of inflammatory postoperative ileus. We sought to determine whether the emerging neuronal modulator COX-2 plays a significant role in primary afferent activation during postoperative ileus using spinal Fos expression as a marker.

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