Affordable Access

deepdyve-link
Publisher Website

COVID-19: beta-thalassemia subjects immunised?

Authors
  • Lansiaux, Edouard1
  • Pébaÿ, Philippe Pierre2
  • Picard, Jean-Laurent3
  • Son-Forget, Joachim4
  • 1 Henry Warembourg Medicine School, Lille University, 59000 Lille, France. Electronic address: edouard.lansiaux.et[email protected] , (France)
  • 2 NexGen Analytics, 82801 Sheridan, WY, United States. , (United States)
  • 3 Conservatoire National des Arts et Métiers, 75141 Paris, France. , (France)
  • 4 Assemblée Nationale, 75355 Paris, France. , (France)
Type
Published Article
Journal
Medical hypotheses
Publication Date
Sep 01, 2020
Volume
142
Pages
109827–109827
Identifiers
DOI: 10.1016/j.mehy.2020.109827
PMID: 32447232
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The novel coronavirus pneumonia (COVID-19) is a contagious acute respiratory infectious disease whose causative agent has been demonstrated to be a novel virus of the coronavirus family, SARSCoV-2. A recent PRE-print study has showed a heme attack on the 1-beta chain of hemoglobin by COVID19. Beta-thalassemia results of a default in the hemoglobin beta-chain synthesis. 1,5% global population are heterozygotes for this disease. In this study, by a multiple linear regression, we have analyzed the evolution of COVID-19 infection in three Italian regions (Puglia, Sardinia, Sicilia) with different beta-thalassemic prevalences, in order to search a link. The results have showed that betathalassemic heterozygote population prevalence is correlated to immunity against COVID-19, by a regression. This paper is only for academic discussion, the hypotheses and conclusions needs to be confirmed by further research. Copyright © 2020 Elsevier Ltd. All rights reserved.

Report this publication

Statistics

Seen <100 times