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Could Borrelia burgdorferi be a causal agent of sarcoidosis?

Authors
Type
Published Article
Journal
Medical Hypotheses
0306-9877
Publisher
Elsevier
Publication Date
Volume
30
Issue
4
Pages
241–243
Identifiers
PMID: 2615685
Source
Medline

Abstract

Sarcoidosis is a multisystem granulomatous disorder of unknown etiology, most commonly affecting young adults presenting most frequently with bilateral hilar lymphadenopathy, pulmonary infiltrations, skin or eye lesions (1). Borrelia burgdorferi, the causal agent of Lyme disease, could also be responsible for sarcoidosis. Domestic animals may play a major role in transmitting the disease to humans. The modes of transmission to such animals and possible contact transmission to humans are still obscure and should be more fully investigated. Small rodents have been found to play a role as reservoirs for Borrelia burgdorferi. They are suspected to constitute an important source of contamination for domestic animals. The author explains in this paper how geographic distribution and familial occurrence of sarcoidosis as well as racial differences in the incidence of this disease, could be related to such findings.

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