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Cortisol hyporesponsiveness to the low dose ACTH test is a frequent finding in a pediatric population with type 1 diabetes mellitus.

Authors
Type
Published Article
Journal
Pediatric Diabetes
1399-5448
Publisher
Wiley Blackwell (Blackwell Publishing)
Publication Date
Volume
14
Issue
6
Pages
429–434
Identifiers
DOI: 10.1111/pedi.12021
PMID: 23490274
Source
Medline
Keywords
License
Unknown

Abstract

We found a significant proportion of our patients having a subnormal cortisol response independent of the presence of anti-adrenal cell antibodies. We did not find a correlation with metabolic control, probably due to the good metabolic control of this group. The absence of 21OHA does not rule out subclinical hypocortisolism in this population. Our results suggest testing adrenal function in children with DM1.

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