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Correlations between serum levels of beta amyloid, cerebrospinal levels of tau and phospho tau, and delayed response tasks in young and aged cynomolgus monkeys (Macaca fascicularis).

Authors
  • Darusman, H S1
  • Sajuthi, D
  • Kalliokoski, O
  • Jacobsen, K R
  • Call, J
  • Schapiro, S J
  • Gjedde, A
  • Abelson, K S P
  • Hau, J
  • 1 Department of Experimental Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark. , (Denmark)
Type
Published Article
Journal
Journal of Medical Primatology
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jun 01, 2013
Volume
42
Issue
3
Pages
137–146
Identifiers
DOI: 10.1111/jmp.12044
PMID: 23530983
Source
Medline
License
Unknown

Abstract

Circulating Aβ42 levels were lower in Aged monkeys and were correlated with inferior performance on delayed response tasks in Aged animals; therefore, both measures may be useful in establishing cynomolgus monkeys as models for studies of AD.

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