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Correlation between the urinary dihydrouracil-uracil ratio and the 5-FU plasma concentration in patients treated with oral 5-FU analogs.

Authors
  • Nakayama, Yoshifumi
  • Matsumoto, Kentaro
  • Inoue, Yuzuru
  • Katsuki, Takefumi
  • Kadowaki, Koji
  • Shibao, Kazunori
  • Tsurudome, Yosuke
  • Hirata, Keiji
  • Sako, Tatsuhiko
  • Nagata, Naoki
  • Itoh, Hideaki
Type
Published Article
Journal
Anticancer research
Publication Date
Jan 01, 2006
Volume
26
Issue
5B
Pages
3983–3988
Identifiers
PMID: 17094430
Source
Medline
License
Unknown

Abstract

Our findings indicate that either urinary Ura, the UH2/Ura or UH2/Ura (treated/no treated) can predict the plasma 5-FU concentration levels or DPD deficiencies.

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