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The correlation between iodine and metabolism: a review

Authors
  • Zhang, Le1
  • Shang, Fangjian2
  • Liu, Cong1
  • Zhai, Xiaodan1
  • 1 Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang , (China)
  • 2 Department of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang , (China)
Type
Published Article
Journal
Frontiers in Nutrition
Publisher
Frontiers Media SA
Publication Date
Mar 19, 2024
Volume
11
Identifiers
DOI: 10.3389/fnut.2024.1346452
Source
Frontiers
Keywords
Disciplines
  • Nutrition
  • Review
License
Green

Abstract

Iodine is involved in the synthesis of thyroid hormones and plays a crucial role in human life. Both iodine deficiency and excess are common issues in certain populations. Iodine also has extrathyroidal effects on organs that can uptake it independently of thyroid hormones. Recently, multiple clinical studies have shown a connection between iodine intake and metabolic disorders, such as metabolic syndrome, obesity, diabetes, hypertension, and dyslipidemia. However, the results of these studies have been inconsistent, and the mechanisms behind these associations are still not well understood. Therefore, in this review, we aim to examine the recent research progress regarding the relationship between iodine and metabolic disorders, along with the relevant mechanisms.

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