Affordable Access

Correlation between Helicobacter pylori OipA Protein Expression and oipA Gene Switch Status

Authors
  • Takahiko Kudo
  • Zhannat Z. Nurgalieva
  • Margaret E. Conner
  • Sue Crawford
  • Stefan Odenbreit
  • Rainer Haas
  • David Y. Graham
  • Yoshio Yamaoka
Publisher
American Society for Microbiology
Publication Date
May 01, 2004
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

Polyclonal antisera to either a synthetic OipA peptide or a recombinant OipA protein detected OipA expression in Helicobacter pylori and correlated with functional oipA status determined by PCR sequence (sensitivity and specificity of >94%). Immunoblotting is a simple and accurate method for detecting expression of the important virulence factor OipA.

Report this publication

Statistics

Seen <100 times