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Coronary stenting in stable patients: identification of a low-risk subgroup that may not require adjunctive antiplatelet therapy.

Authors
  • Mann, Tift
  • Cubeddu, Roberto J
  • Raynor, Laura
  • Bowen, Josie
  • Schneider, Joel E
  • Rose, Gregory
  • Cubeddu, Gabriela
  • Raza, Jaffar Ali
  • Jobe, Robert Lee
  • Newman, William
  • Zellinger, Micheal
Type
Published Article
Journal
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Publication Date
Apr 01, 2003
Volume
58
Issue
4
Pages
459–466
Identifiers
PMID: 12652495
Source
Medline
License
Unknown

Abstract

The present study prospectively evaluated adjunctive antiplatelet therapy in patients without insulin-requiring diabetes during elective coronary stenting. Three hundred patients were randomized to one of three treatment groups: clopidogrel pretreatment, adjunctive abciximab, or control. Stenting was successful in 98% and no deaths occurred. Thirty-day and 1-year major adverse coronary events (MACEs) was similar in all groups. A subgroup of 109 patients undergoing single-vessel stenting of type A/B1 lesions with short guidewire times had no postprocedure myocardial infarction or 30-day MACE. We conclude that patients with these characteristics may safely undergo elective coronary stenting without adjunctive antiplatelet therapy.

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