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Corneal Penetrating Elastin-Like Polypeptide Carriers.

Authors
  • George, Eric M1, 2
  • Mahdi, Fakhri3
  • Logue, Omar C3
  • Robinson, Grant G3
  • Bidwell, Gene L 3rd2, 3
  • 1 1 Department of Physiology and Biophysics, University of Mississippi Medical Center , Jackson, Mississippi.
  • 2 2 Department of Biochemistry, University of Mississippi Medical Center , Jackson, Mississippi.
  • 3 3 Department of Neurology University of Mississippi Medical Center , Jackson, Mississippi.
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
April 2016
Volume
32
Issue
3
Pages
163–171
Identifiers
DOI: 10.1089/jop.2015.0082
PMID: 26672799
Source
Medline
License
Unknown

Abstract

The ELP drug carrier can penetrate the corneal epithelium and accumulate in the stroma. Given its amenability for fusion to multiple types of therapeutic agents, ELP has the potential to serve as a drug carrier for topical ocular applications.

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