The core-inversible micelles for hydrophilic drug delivery.
- Authors
- Type
- Published Article
- Journal
- Chemical Communications
- Publisher
- The Royal Society of Chemistry
- Volume
- 49
- Issue
- 59
- Pages
- 6674–6676
- Identifiers
- DOI: 10.1039/c3cc43209b
- Source
- Kit Lam Lab
- License
- Unknown
Abstract
A unique core-inversible micelle (CIM) was formed via PEG(5k)CA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.
