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A controlled crossover study of triiodothyronine in autistic children.

Authors
  • Campbell, M
  • Small, A M
  • Hollander, C S
  • Korein, J
  • Cohen, I L
  • Kalmijn, M
  • Ferris, S
Type
Published Article
Journal
Journal of autism and childhood schizophrenia
Publication Date
Dec 01, 1978
Volume
8
Issue
4
Pages
371–381
Identifiers
PMID: 365855
Source
Medline
License
Unknown

Abstract

A placebo-controlled crossover study of behavioral effects of triiodothyronine (T3) was conducted in 30 young clinically euthyroid autistic children. Multiple independent raters and multiple rating scales were used. Except for a few symptoms that were reduced on T3, the drug did not differ from placebo. Time itself accounted for most of the improvement in the whole sample. As a group, the lower IQ children responded to T3. The individual children who were responders could not be defined by any parameter.

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