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Contributions of fat and protein to the incretin effect of a mixed meal.

Authors
  • Carrel, Guillaume1
  • Egli, Léonie
  • Tran, Christel
  • Schneiter, Philippe
  • Giusti, Vittorio
  • D'Alessio, David
  • Tappy, Luc
  • 1 Department of Physiology, University of Lausanne, Lausanne, Switzerland. , (Switzerland)
Type
Published Article
Journal
American Journal of Clinical Nutrition
Publisher
Oxford University Press
Publication Date
October 2011
Volume
94
Issue
4
Pages
997–1003
Identifiers
DOI: 10.3945/ajcn.111.017574
PMID: 21849595
Source
Medline
License
Unknown

Abstract

Fat ingestion, in an amount typical of a standard meal, increases insulin secretion during physiologic hyperglycemia and thus contributes to the incretin effect. In contrast, ingestion of protein typical of normal meals does not contribute to the augmentation of postprandial insulin secretion. This trial was registered at clinicaltrials.gov as NCT00869453.

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