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Contribution of Therapeutic Monitoring in the Assessment of Toxic Adverse Effects of Mitotane: a Case Report

Authors
  • Jebabli, Nadia
  • Gaïes, Emna
  • Eljebari, Hanen
  • Charfi, Rim
  • Lakhal, Mohamed
  • Klouz, Anis
  • Salouage, Issam
  • Trabelsi, Sameh
Type
Published Article
Journal
Thérapie
Publisher
Elsevier
Publication Date
Aug 04, 2015
Volume
70
Issue
6
Pages
545–546
Identifiers
DOI: 10.2515/therapie/2015043
Source
EDP Sciences
Keywords
License
White

Abstract

Mitotane provided serious side effects and low doses seemed to be tolerated. Determination of mitotane concentration in plasma is recommended. We report the case of toxic plasma levels with low doses of mitotane in a 47-year-old man with adrenocortical cancer.

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