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Contribution of symmetric dimethylarginine to GFR decline in pediatric chronic kidney disease.

Authors
  • Brooks, Ellen R1, 2
  • Haymond, Shannon3, 4
  • Rademaker, Alfred3, 5
  • Pierce, Christopher6
  • Helenowski, Irene3, 5
  • Passman, Rod3, 7
  • Vicente, Faye4
  • Warady, Bradley A8
  • Furth, Susan L9
  • Langman, Craig B3, 10
  • 1 Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. [email protected]
  • 2 Division of Kidney Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Mailstop # 37, 225 E. Chicago Ave, Chicago, IL, 60611, USA. [email protected]
  • 3 Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • 4 Department of Pathology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • 5 Division of Biostatistics, Department of Preventive Medicine, Feinberg School of Medicine, Chicago, IL, USA.
  • 6 Department of Epidemiology, University Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • 7 Division of Cardiology, Department of Internal Medicine, Northwestern Medical Group, Chicago, IL, USA.
  • 8 Division of Pediatric Nephrology, The Children's Mercy Hospital, Kansas City, MO, USA.
  • 9 Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • 10 Division of Kidney Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Mailstop # 37, 225 E. Chicago Ave, Chicago, IL, 60611, USA.
Type
Published Article
Journal
Pediatric Nephrology
Publisher
Springer-Verlag
Publication Date
Apr 01, 2018
Volume
33
Issue
4
Pages
697–704
Identifiers
DOI: 10.1007/s00467-017-3842-x
PMID: 29214443
Source
Medline
Keywords
License
Unknown

Abstract

In pCKD, higher concentrations of BL MADs were inversely related to BL mGFR. MADs did not affect the CKD progression rate. Quantification of this relationship is novel to the pCKD literature.

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