Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Contribution of each complex of the mitochondrial respiratory chain in the generation of the proton-motive force*.

Authors
  • Garcia-Vallve, Santiago
Type
Published Article
Journal
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
Publication Date
Jan 01, 2004
Volume
32
Issue
1
Pages
17–19
Identifiers
DOI: 10.1002/bmb.2004.494032010308
PMID: 21706682
Source
Medline
License
Unknown

Abstract

A new parameter is presented for considering the contribution from each complex of the mitochondrial respiratory chain to the creation of the electrochemical gradient. This parameter is the proton gradient generated in each complex per pair of electrons transported (ΔH(+) /2e(-) ) and may be calculated as the sum of the electrons taken up from the N-side and the electrons released at the P-side. The ΔH(+) /2e(-) values take into account all the electrons taken up and released in each complex and differentiate between the contribution from protons that are translocated from the N-side to the P-side and the contribution of scalar protons. Using these values, the P/O ratios for the oxidation of NADH and succinate are predicted to be 2.5 and 1.5, respectively.

Report this publication

Statistics

Seen <100 times