Bottom-up energy models are considered essential tools to support policy design of electricity end-use efficiency. However, in the literature, no study analyzes their contribution to support policy design of electricity end-use efficiency, the modeling techniques used to build them, and the policy instruments supported by them. This systematic review fills that gap by identifying the current capability of bottom-up energy models to support specific policy instruments. In the research, we review 192 publications from January 2015 to June 2020 to finally select 20 for further examination. The articles are analyzed quantitatively in terms of techniques, model characteristics, and applied policies. The findings of the study reveal that: (1) bottom-up energy models contribute to the support of policy design of electricity end-use efficiency with the application of specific best practices (2) bottom-up energy models do not provide a portfolio of analytical methods which constraint their capability to support policy design (3) bottom-up energy models for residential buildings have limited policy support and (4) bottom-up energy models’ design reveals a lack of inclusion of key energy efficiency metrics to support decision-making. This study’s findings can help researchers and energy modelers address these limitations and create new models following best practices.