Affordable Access

deepdyve-link
Publisher Website

Contribution of 18F-FDG PET/CT in the Differential Diagnosis of Pulmonary Hamartomas and Pulmonary Carcinoids

Authors
  • Tatcı, Ebru1
  • Özmen, Özlem1
  • Öztürk, Ayperi2
  • Demirağ, Funda3
  • 1 University of Health Sciences Turkey, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Clinic of Nuclear Medicine, Ankara, Turkey
  • 2 University of Health Sciences Turkey, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Clinic of Interventional Pulmonology, Ankara, Turkey
  • 3 University of Health Sciences Turkey, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Clinic of Pathology, Ankara, Turkey
Type
Published Article
Journal
Molecular Imaging and Radionuclide Therapy
Publisher
Galenos Publishing
Publication Date
Jun 03, 2021
Volume
30
Issue
2
Pages
101–106
Identifiers
DOI: 10.4274/mirt.galenos.2021.20633
PMID: 34082511
PMCID: PMC8185474
Source
PubMed Central
Keywords
Disciplines
  • Original Article
License
Unknown

Abstract

Objectives: This study aimed to evaluate 18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) findings in the differential diagnosis of pulmonary carcinoids and pulmonary hamartomas. Methods: 18F-FDG PET/CT findings of 34 patients with pulmonary carcinoids (12 atypical, 22 typical) and 32 patients with pulmonary hamartomas were retrospectively evaluated. Both mean diameter and mean maximum standardized uptake value (SUVmax) of hamartomas and carcinoids were compared by Mann-Whitney U and Kruskall-Wallis H tests. Results: The mean longest diameter of atypical carcinoids (3.5±1.7 cm) was higher than that of hamartomas (2.1±1 cm) (p=0.038). No significant difference was found between the mean diameter of typical carcinoids and mean diameter of hamartomas (p=0.128). The mean SUVmax of atypical carcinoids (5.97±3.7) and typical carcinoids (4.22±1.7) were higher than those of hamartomas (1.65±0.9) (p=0.002 and p=0.003, respectively). There were collapse/consolidation in 55.8%, bronchiectasis or mucoid impaction in 47%, and air trapping in 14.7% in the peripheral parenchyma of the 34 carcinoids. Collapse/consolidation was detected in a patient with endobronchial hamartoma, and other finding was not found in the parenchyma around hamartomas. Conclusion: The 18F-FDG uptake of pulmonary carcinoids can vary from minimal to intense. 18F-FDG uptake can be seen in pulmonary hamartomas. However, the mean SUVmax of atypical carcinoids and typical carcinoids were higher compared to hamartomas. Pulmonary carcinoid must be suspected in cases with accompanying bronchial obstruction findings in the periphery of the mass.

Report this publication

Statistics

Seen <100 times