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Continuous cyclic load reduces proteoglycan release from articular cartilage.

Authors
  • Torzilli, P A
  • Grigiene, R
Type
Published Article
Journal
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Publication Date
Jul 01, 1998
Volume
6
Issue
4
Pages
260–268
Identifiers
PMID: 9876395
Source
Medline
License
Unknown

Abstract

These results indicate that PG release from the cartilage matrix is inhibited by continuous cyclic mechanical loading, independent of cellular metabolism, and suggest that a primary mechanism for reducing PG release is by decreasing the interstitial porosity through which the PGs can escape.

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