Affordable Access

[Continuous cell subline A4C2/9K and its application to the african swine fever virus study].

Authors
  • Balysheva, V I
  • Prudnikova, E Yu
  • Galnbek, T V
  • Balyshev, V M
Type
Published Article
Journal
Voprosy virusologii
Publication Date
Jan 01, 2015
Volume
60
Issue
2
Pages
43–47
Identifiers
PMID: 26182658
Source
Medline
License
Unknown

Abstract

A new continuous cell subline A4C2/9K highly sensitive to the african swine fever virus (ASFV) was prepared. All the tested ASFV strains isolated in the Russian Federation in 2008-2013 proliferated in this cell culture exhibiting hemadsorption and accumulated at a titer of up to 6.5 Ig HAU50/cm3. The cell culture A4C2/9K can be used for ASFV isolation or determination of its infectious activity and serotype identity. The culture versions of the ASFV strain Stavropol 01/08 at passages 24 and 33 in the cell culture A4C2/9K lost their pathogenicity for pigs.

Report this publication

Statistics

Seen <100 times