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Contemporary diagnostics: sarcoma pathology update.

Authors
  • Brooks, John S J
  • Lee, Solomon
Type
Published Article
Journal
Journal of Surgical Oncology
Publisher
Wiley (John Wiley & Sons)
Publication Date
Apr 01, 2015
Volume
111
Issue
5
Pages
513–519
Identifiers
DOI: 10.1002/jso.23853
PMID: 25689920
Source
Medline
Keywords
License
Unknown

Abstract

Sarcoma diagnosis continues to evolve as new information is discovered. Certain tumors have been downgraded (dermal leiomyosarcoma) and an atypical category designed for others. Recently entities include myxoinflammatory fibroblastic sarcoma, myoepithelioma, and pseudomyogenic hemangioendothelioma. The terms malignant fibrous histiocytoma and hemangiopericytoma are outdated. New immunostains (STAT6, SOX10, ERG) add diagnostic specificity, and new risk assessment models are described for sarcomas where grading and staging has failed to provide adequate prognosis.

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