Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Conservative treatment of a pathological fracture in a 3-year-old boy with primary hyperoxaluria type I.

Authors
  • Dierselhuis, Edwin F
  • Maathuis, Patrick G M
Type
Published Article
Journal
Journal of pediatric orthopedics. Part B
Publication Date
Mar 01, 2013
Volume
22
Issue
2
Pages
175–177
Identifiers
DOI: 10.1097/BPB.0b013e32834fe880
PMID: 22215125
Source
Medline
License
Unknown

Abstract

Primary hyperoxaluria type I is a rare inherited disease that presents a disturbed metabolism of glyoxylate. Consequently, patients suffer from hyperoxaluria, leading to renal failure and subsequent skeletal calcium oxalate deposition. Areas with high concentrations of calcium oxalate, so-called dense metaphyseal bands, are at risk for pathological fracturing. The primary disease is treated by combined liver-kidney transplantation, although pathological fracturing also occurs in the posttransplant period. In the current case, we present a 3-year-old boy with a pathological fracture of his right femur, 2 years after liver-kidney transplantation. We opted for a conservative regime, leading to good fracture healing. As there are limited data in the literature regarding treatment of fractures in these patients, it is important to notify the outcome of conservative treatment of pathological fractures in patients with primary hyperoxaluria type I.

Report this publication

Statistics

Seen <100 times