Affordable Access

Congenital factor XIII deficiency with multiple benign breast tumours and successful pregnancy with substitutive therapy. A case report.

Authors
  • Boda, Z
  • Pfliegler, G
  • Muszbek, L
  • Tóth, A
  • Adány, R
  • Hársfalvi, J
  • Papp, Z
  • Tornai, I
  • Rak, K
Type
Published Article
Journal
Haemostasis
Publication Date
Jan 01, 1989
Volume
19
Issue
6
Pages
348–352
Identifiers
PMID: 2620871
Source
Medline
License
Unknown

Abstract

A 34-year-old woman with congenital factor XIII (FXIII) deficiency and multiple connective tissue tumours is reported. The subunit a of FXIII was totally absent in her plasma, platelets and histiocytes of breast fibroadenomas and considerably reduced in the monocytes (below 5%). The plasmatic level of subunit b was also reduced (25%). She had a bleeding tendency and habitual abortions. Fresh frozen plasma therapy permitted a successful pregnancy.

Report this publication

Statistics

Seen <100 times