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Confounding factors of non-invasive tests for nonalcoholic fatty liver disease

Authors
  • Wai, Janae Wentong1
  • Fu, Charmaine1
  • Wong, Vincent Wai-Sun1, 1
  • 1 The Chinese University of Hong Kong,
Type
Published Article
Journal
Journal of Gastroenterology
Publisher
Springer Singapore
Publication Date
May 25, 2020
Volume
55
Issue
8
Pages
731–741
Identifiers
DOI: 10.1007/s00535-020-01686-8
PMID: 32451628
PMCID: PMC7376510
Source
PubMed Central
Keywords
License
Unknown

Abstract

Nonalcoholic fatty liver disease (NAFLD) affects at least 25% of the general adult population worldwide. Because only a fraction of the patients would develop liver-related complications, it is preferable to perform non-invasive tests as the initial assessment. This review summarizes the known and potential confounding factors that affect the performance of non-invasive tests of hepatic steatosis and fibrosis in patients with NAFLD. Clinicians may apply the knowledge and exercise caution in selecting investigations and interpreting test results when confounding factors are present.

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