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Confirmation that catalase is a glycoprotein.

Authors
Type
Published Article
Journal
Biochemistry international
Publication Date
Volume
12
Issue
6
Pages
831–838
Identifiers
PMID: 3017350
Source
Medline

Abstract

Catalases which had been purified from the livers of mouse, rat and guinea pig were subjected to mild periodate oxidation followed by reduction with sodium boro[3H]hydride in order to test for the presence of sialic acid. A radioactively labelled moiety resulted, which behaved as a derivative of N-acetyl neuraminic acid during mild acid hydrolysis, neuraminidase treatment, ion exchange chromatography and paper chromatography. It is concluded that mammalian catalases are glycoproteins, and possess variable amounts of N-acetyl neuraminic acid in their carbohydrate moiety.

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