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Cone structure imaged with adaptive optics scanning laser ophthalmoscopy in eyes with nonneovascular age-related macular degeneration.

Authors
  • Zayit-Soudry, Shiri
  • Duncan, Jacque L
  • Syed, Reema
  • Menghini, Moreno
  • Roorda, Austin J
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Nov 01, 2013
Volume
54
Issue
12
Pages
7498–7509
Identifiers
DOI: 10.1167/iovs.13-12433
PMID: 24135755
Source
Medline
Keywords
License
Unknown

Abstract

Adaptive optics scanning laser ophthalmoscopy provides adequate resolution for quantitative measurement of cone spacing at the margin of GA and over drusen in eyes with AMD. Although cone spacing was often normal at baseline and remained normal over time, these regions showed focal areas of decreased cone reflectivity. These findings may provide insight into the pathophysiology of AMD progression. (ClinicalTrials.gov number, NCT00254605).

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