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Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients.

Authors
  • Smith, Geoffrey A
  • Levinson, Anya L
  • Galvin, Robert T
  • Lalor, Leah E
  • McCalmont, Timothy
  • Wang, Linlin
  • Geis, Michael C
  • Odegaard, Karah
  • Hupp, Meghan
  • Maguiness, Sheilagh
  • Turcotte, Lucie M
  • Cordoro, Kelly M
  • Hermiston, Michelle L
Publication Date
Aug 01, 2021
Source
eScholarship - University of California
Keywords
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Unknown
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Abstract

Subcutaneous panniculitis-like T-cell lymphoma is a cutaneous lymphoma characterized by CD8+ T-cell infiltrate in the subcutis that is rare in children. Acute lymphoblastic lymphoma is the most common pediatric malignancy and often presents with fevers and pancytopenia. Herein, we report 2 pediatric patients presenting with subcutaneous panniculitis-like T-cell lymphoma and B-cell acute lymphoblastic lymphoma, distinct hematologic malignancies arising from different lymphoid lineages, with no identifiable germline cancer predisposition.

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