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A conceptual protocol for translational research in the complex reality of leprosy.

Authors
  • Kuipers, Pim
  • Rao, P S S
  • Raju, M S
  • John, Annamma S
  • Sabuni, Louis Paluku
Type
Published Article
Journal
Leprosy Review
Publisher
GN1 Genesis Network
Publication Date
Jun 01, 2013
Volume
84
Issue
2
Pages
166–174
Identifiers
PMID: 24171245
Source
Medline
License
Unknown

Abstract

In response to an international strategy to prioritise and focus research efforts in leprosy, this conceptual protocol outlines a research plan to address key translational research priorities. The protocol describes in broad terms a five-phase psychosocial and service-related research programme to facilitate: prevention of delay in diagnosis, improvement of adherence with multi-drug therapy, the roll out of chemoprophylaxis and increased participation in community based rehabilitation. The protocol proposes a model of research utilisation and the notion of complexity to form an integrating theoretical framework for exploring and enhancing research translation. The proposed sequential research programme is characterised by traditional and participatory strategies, culminating in participatory implementation of findings. Publication of the conceptual protocol prior to operationalisation and commencement of the research aims to encourage debate, refinement of strategies, collaboration and the optimisation of resources.

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