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Computational approaches to unveiling ancient genome duplications

Authors
  • Van de Peer, Yves
Publication Date
Jan 01, 2004
Identifiers
DOI: 10.1038/nrg1449
OAI: oai:archive.ugent.be:298760
Source
Ghent University Institutional Archive
Keywords
Language
English
License
Unknown
External links

Abstract

Recent analyses of complete genome sequences have revealed that many genomes have been duplicated in their evolutionary past. Such events have been associated with important biological transitions, major leaps in evolution and adaptive radiations of species. Here, we consider recently developed computational methods to detect such ancient large-scale gene duplication events. Several new approaches have been used to show that large-scale gene duplications are more common than previously thought.

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